72
Participants
Start Date
December 1, 2021
Primary Completion Date
August 31, 2026
Study Completion Date
August 31, 2026
Mechanical unloading of the Thorax using an external cuirass
External cuirass (i.e., a plastic shell over the thorax) will be used to mechanically unload the chest wall. The cuirass has different operating modes. It can generate a constant negative pressure over the chest wall (e.g., -20cmH2O) or it can be triggered off mouth flow so it can generate a negative pressure on the chest wall during inspiration (e.g., -21cmH2O) and a positive pressure during expiration (e.g., +7cmH2O).
RECRUITING
Institute for Exercise and Environmental Medicine, UT Southwestern and Texas Health Resources, Dallas
National Institute on Aging (NIA)
NIH
University of Texas Southwestern Medical Center
OTHER