Effects of Obesity in the Aged

NARecruitingINTERVENTIONAL
Enrollment

72

Participants

Timeline

Start Date

December 1, 2021

Primary Completion Date

August 31, 2026

Study Completion Date

August 31, 2026

Conditions
ObesityAging
Interventions
OTHER

Mechanical unloading of the Thorax using an external cuirass

External cuirass (i.e., a plastic shell over the thorax) will be used to mechanically unload the chest wall. The cuirass has different operating modes. It can generate a constant negative pressure over the chest wall (e.g., -20cmH2O) or it can be triggered off mouth flow so it can generate a negative pressure on the chest wall during inspiration (e.g., -21cmH2O) and a positive pressure during expiration (e.g., +7cmH2O).

Trial Locations (1)

75231

RECRUITING

Institute for Exercise and Environmental Medicine, UT Southwestern and Texas Health Resources, Dallas

All Listed Sponsors
collaborator

National Institute on Aging (NIA)

NIH

lead

University of Texas Southwestern Medical Center

OTHER