Fenfluramine and Cognition

PHASE4CompletedINTERVENTIONAL
Enrollment

56

Participants

Timeline

Start Date

April 12, 2021

Primary Completion Date

June 22, 2022

Study Completion Date

June 22, 2022

Conditions
Cognitive Function
Interventions
DRUG

Fenfluramine

Fenfluramine (30mg daily) will be dispensed in a cherry flavoured aqueous solution. Fenfluramine is both a serotonin releasing agent and sigma-1 receptor agonist. Fenfluramine is FDA approved for the treatment of Dravet syndrome, a rare form of epilepsy.

OTHER

Placebo

The placebo is a liquid designed to be identical to the interventional drug fenfluramine in terms of both taste and visual appearance. It will be administered at 30mg daily and dispensed in a cherry flavoured aqueous solution

Trial Locations (1)

Unknown

Department of Psychiatry, University of Oxford, Oxford

All Listed Sponsors
collaborator

Zogenix International Limited, Inc., a subsidiary of Zogenix, Inc.

INDUSTRY

collaborator

National Institute for Health Research, United Kingdom

OTHER_GOV

lead

University of Oxford

OTHER