Real-time fMRI Neurofeedback for Mild/Moderate Depression

Real-time fMRI neurofeedback targeting control of the left medial prefrontal cortex. Participants continuously received visual feedback on the level of activity within the 2D region of interest corrected to the whole-slice brain volume activity. Up- and downregulation blocks were switched for better control.

A combination of individual and small-group cognitive behavioral therapy by an experienced medical psychologist and a psychiatrist.

EEG neurofeedback targeting frontal alpha asymmetry index. Participants continuously received visual feedback on their frontal alpha asymmetry index. Up-regulation condition only was utilized.