Cardiovascular Injury and Cardiac Fitness in Locally Advanced Non-Small Cell Lung Cancer Patients Receiving Model Based Personalized Chemoradiation

PHASE1RecruitingINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

July 5, 2021

Primary Completion Date

February 23, 2026

Study Completion Date

February 23, 2026

Conditions
Locally Advanced Lung Non-Small Cell CarcinomaStage III Lung Cancer AJCC v8Stage IIIA Lung Cancer AJCC v8Stage IIIB Lung Cancer AJCC v8Stage IIIC Lung Cancer AJCC v8
Interventions
PROCEDURE

6 Minute Walk Functional Test

Participate in 6 MWT

PROCEDURE

Biospecimen Collection

Undergo blood and urine sample collection

PROCEDURE

Computed Tomography

Undergo SPECT/CT

PROCEDURE

Echocardiography

Undergo echocardiogram

PROCEDURE

Exercise Cardiac Stress Test

Undergo stress test

OTHER

Questionnaire Administration

Complete questionnaires

PROCEDURE

Single Photon Emission Computed Tomography

Undergo SPECT/CT

Trial Locations (1)

77030

RECRUITING

M D Anderson Cancer Center, Houston

All Listed Sponsors
collaborator

National Heart, Lung, and Blood Institute (NHLBI)

NIH

lead

M.D. Anderson Cancer Center

OTHER