A Study of Reduced-dose Radiation in People With Metastatic Tumors With a Genetic Change

PHASE2RecruitingINTERVENTIONAL
Enrollment

29

Participants

Timeline

Start Date

August 11, 2021

Primary Completion Date

August 31, 2026

Study Completion Date

August 31, 2026

Conditions
Metastatic Cancer
Interventions
RADIATION

Palliative radiotherapy

An initial cohort of 12 evaluable patients will be treated with 4Gyx2, with adaptive dosing planned for expansion cohorts pending the number of failures observed after 6 month observation of the initial cohort.

Trial Locations (7)

10065

RECRUITING

Memorial Sloan Kettering Basking Ridge (All Protocol Activities), Basking Ridge

RECRUITING

Memorial Sloan Kettering Cancer Center (All Protocol Activities), New York

10604

RECRUITING

Memorial Sloan Kettering Westchester (All Protocol Activities), Harrison

11553

RECRUITING

Memorial Sloan Kettering Nassau (All protocol activities), Uniondale

11725

RECRUITING

Memorial Sloan Kettering Commack (All protocol activities), Commack

07748

RECRUITING

Memorial Sloan Kettering Monmouth (All protocol activities), Middletown

07645

RECRUITING

Memorial Sloan Kettering Bergen (All protocol activities), Montvale

All Listed Sponsors
lead

Memorial Sloan Kettering Cancer Center

OTHER