604
Participants
Start Date
March 14, 2022
Primary Completion Date
February 28, 2024
Study Completion Date
February 28, 2024
Toe Brachial Pressure Index (TBPI)
TBPI will be measured using the photoplethysmography (PPG) method, employing an infrared sensor placed on the hallux and index finger.
Ankle Brachial Pressure Index (ABPI)
A sphygmomanometer-cuff placed at the ankle and a handheld continuous wave Doppler device will be used to measure the systolic pressure of the dorsalis pedis and posterior tibial artery.
Exercise Ankle Brachial Pressure Index (ABPI)
A sphygmomanometer-cuff placed at the ankle and a handheld continuous wave Doppler device will be used to measure the systolic pressure of the dorsalis pedis and posterior tibial artery, following the participant completing 50 consecutive repetitions of active dorsiflexion whilst standing.
Audible handheld Doppler
Audible CW Doppler interrogation of the dorsalis pedis and posterior tibial artery.
Visual handheld Doppler
Visual CW interrogation of the dorsalis pedis and posterior tibial artery was performed using the handheld Huntleigh Digital Dopplex device.
Podiatry Ankle Duplex scan (PAD-scan)
"Podiatry ankle duplex scan (PAD-scan) involves using an ultrasound machine to visualise the anterior and posterior tibial arteries at the ankle.~To be used in 3 participating centers only."
Mid and South Essex NHS Foundation Trust, Basildon
Cardiff and Vale UHB, Cardiff
University Hospitals of Derby and Burton NHS Foundation Trust, Derby
NHS Greater Glasgow and Clyde, Glasgow
Hull University Teaching Hospitals NHS Trust, Hull
University Hospitals of Leicester NHS Trust, Leicester
Central London Community Healthcare NHS Trust sites, London
Chelsea and Westminster Hospital NHS Foundation Trust, London
St George's University Hospitals NHS Foundation Trust, London
Imperial College Healthcare NHS Trust, London
Hammersmith and Fulham Partnership, London
South Tees Hospitals NHS Foundation Trust, Middlesbrough
Nottingham University Hospitals (NUH) NHS Trust, Nottingham
Oxford University Hospitals NHS Foundation Trust, Oxford
University Hospitals Plymouth NHS Trust, Plymouth
University Hospitals Southampton NHS Foundation Trust, Southampton
Worcestershire Acute Hospitals NHS Trust, Worcester
University of Leicester
OTHER
University of Edinburgh
OTHER
Universidad de Granada
OTHER
Imperial College London
OTHER