Compare the Efficacy and Safety of HLX04-O with Ranibizumab in Subjects with WAMD

PHASE3CompletedINTERVENTIONAL
Enrollment

407

Participants

Timeline

Start Date

November 1, 2021

Primary Completion Date

May 7, 2024

Study Completion Date

May 7, 2024

Conditions
Age Related Macular Degeneration
Interventions
DRUG

HLX04-O,recombinant anti-vascular endothelial growth factor (VEGF) humanized monoclonal antibody ophthalmic injection

0.05mL solution at a 4-week interval for intravitreal injection

DRUG

Lucentis

0.05mL solution at a 4-week interval for intravitreal injection

Trial Locations (41)

200233

Shanghai General Hospital, Shanghai

Unknown

The first affiliated hospital of bengbu medical college, Bengbu

The Second Affiliated Hospital of Anhui Medical University, Hefei

Beijing Tongren Hospital, Capital Medical University, Beijing

Chinese PLA General Hospital, Beijing

Xuanwu Hospital, Capital Medical University, Beijing

The First Affiliated Hospital of Third Military Medical University (Southwest Hospital), Chongqing

The Second Affiliated Hospital of Chongqing Medical University, Chongqing

The Second Hospital of Lanzhou University, Lanzhou

The First Affiliated Hospital of Jinan University (Guangzhou Overseas Chinese Hospital ), Guangzhou

Zhujiang Hospital of Southern Medical University, Guangzhou

Jieyang People's Hospital, Jieyang

The First Affiliated Hospital of Guangxi Medical University, Nanjing

The People's Hospital of Guangxi Zhuang Autonomous Region, Nanning

Affiliated Hospital of Guizhou Medical University, Guiyang

The First People's Hospital of Zunyi, Zunyi

Cangzhou Central Hospital, Cangzhou

The First Affiliated Hospital of Harbin Medical University, Harbin

Luoyang Third People's Hospital, Luoyang

The First Affiliated Hospital of Xinxiang Medical College, Xinxiang

The Third Affiliated Hospital of Xinxiang Medical College, Xinxiang

Henan Eye Hospital, Zhengzhou

People's Hospital of Wuhan University (Hubei Provincial People's Hospital), Wuhan

Tongji hospital, Tongji medical college, Huazhong University of Science and Technology, Wuhan

Wuhan AIER Eye Hospital, Wuhan

Wuhan Puren Hospital, Wuhan

Yichang Central People's Hospital, Yichang

Affiliated Eye Hospital of Nanchang University, Nanchang

the First Affiliated Hospital of Nanchang University, Nanchang

Pingxiang People's Hospital, Pingxiang

The First Hospital of Jilin University, Jilin

Shenyang AIER Eye Hospital, Shenyang

Ningxia Hui Autonomous Region Peoples Hospital, Yinchuan

Shangdong Provincial Hospital, Jinan

The Affiliated Hospital of Qingdao University, Qingdao

Weifang Eye Hospital, Weifang

Shanghai Tenth People's Hospital, Shanghai

Shanxi Eye Hospital, Taiyuan

Tianjin Eye Hospital, Tianjin

Zhejiang provincial people's hospital, Hangzhou

Lishui Municioal Central Hospital, Lishui

All Listed Sponsors
lead

Shanghai Henlius Biotech

INDUSTRY

NCT05003245 - Compare the Efficacy and Safety of HLX04-O with Ranibizumab in Subjects with WAMD | Biotech Hunter | Biotech Hunter