A Study to Assess Adjuvant Immunotherapy With Nivolumab Plus Relatlimab Versus Nivolumab Alone After Complete Resection of Stage III-IV Melanoma

PHASE3TerminatedINTERVENTIONAL
Enrollment

1,190

Participants

Timeline

Start Date

October 19, 2021

Primary Completion Date

December 16, 2024

Study Completion Date

April 2, 2025

Conditions
Melanoma
Interventions
BIOLOGICAL

Nivolumab

Specified dose on specified days

BIOLOGICAL

Nivolumab + Relatlimab Fixed Dose Combination

Specified dose on specified days

Trial Locations (184)

1090

Local Institution - 0084, Vienna

Local Institution - 0110, Brussels

1200

Local Institution - 0105, Brussels

1426

Local Institution - 0005, Buenos Aires

1478

Local Institution - 0009, Lørenskog

2065

Local Institution - 0032, Wollstonecraft

2145

Local Institution - 0252, Westmead

2298

Local Institution - 0030, Waratah

2610

Local Institution - 0106, Wilrijk

2730

Local Institution - 0018, Copenhagen

3000

Local Institution - 0031, Melbourne

3084

Local Institution - 0253, Heidelberg

3350

Local Institution - 0035, Ballarat

4000

Local Institution - 0109, Liège

4011

Local Institution - 0023, Stavanger

4031

Local Institution - 0085, Basel

4102

Local Institution - 0028, Brisbane

4215

Local Institution - 0027, Southport

5000

Local Institution - 0020, Odense

5011

Local Institution - 0250, Woodville

5020

Local Institution - 0086, Salzburg

6009

Local Institution - 0029, Perth

6150

Local Institution - 0251, Murdoch

7000

Local Institution - 0087, Chur

8036

Local Institution - 0082, Graz

8091

Local Institution - 0090, Zurich

8200

Local Institution - 0016, Aarhus

9100

Local Institution - 0022, Aalborg

10016

Local Institution - 0140, New York

10029

Icahn School Of Medicine At Mount Sinai, New York

10065

Local Institution - 0210, New York

11527

Local Institution - 0114, Athens

12808

Local Institution - 0062, Prague

13385

Local Institution - 0044, Marseille

15232

Local Institution - 0125, Pittsburgh

18012

Local Institution - 0153, Granada

18103

Local Institution - 0267, Allentown

19111

Fox Chase Cancer Center, Philadelphia

20007

Local Institution - 0166, Washington D.C.

20014

Local Institution - 0151, Donostia / San Sebastian

20133

Local Institution - 0115, Milan

Local Institution - 0268, Milan

20141

Local Institution - 0123, Milan

20521

Local Institution - 0015, Turku

21000

Local Institution - 0043, Dijon

21614

Local Institution - 0073, Buxtehude

22031

Local Institution - 0137, Fairfax

23538

Local Institution - 0078, Lübeck

27710

Local Institution - 0145, Durham

28009

Local Institution - 0150, Madrid

28204

Local Institution - 0130, Charlotte

29425

Local Institution - 0171, Charleston

30322

Local Institution - 0191, Atlanta

30342

Local Institution - 0148, Atlanta

30625

Local Institution - 0079, Hanover

31100

Local Institution - 0046, Toulouse

32429

Local Institution - 0083, Minden

32504

Local Institution - 0179, Pensacola

33136

Local Institution - 0243, Miami

Washington University School Of Medicine, Miami

33520

Local Institution - 0019, Tampere

33612

Moffitt Cancer Center, Richard M. Shulze Family Foundation Outpatient Center, Tampa

35128

Local Institution - 0120, Padua

35249

Local Institution - 0176, Birmingham

37232

Local Institution - 0183, Nashville

38138

Local Institution - 0147, Germantown

41345

Local Institution - 0010, Gothenburg

43210

The James Cancer Hospital and Solove Research Institute at The Ohio State University Comprehensive C, Columbus

44093

Local Institution - 0039, Nantes

44109

MetroHealth Medical Center, Cleveland

44195

Local Institution - 0141, Cleveland

45070

Local Institution - 0021, Zapopan

45147

Local Institution - 0131, Essen

46026

Local Institution - 0152, Valencia

46804

Local Institution - 0223, Fort Wayne

48109

Local Institution - 0258, Ann Arbor

49503

Local Institution, Grand Rapids

50005

Local Institution - 0091, Hradec Králové

52242

University of Iowa-Holden Comprehensive Cancer Center, Iowa City

53100

Local Institution - 0121, Siena

55407

Local Institution - 0133, Minneapolis

60611

Local Institution - 0202, Chicago

61615

Local Institution - 0177, Peoria

64320

Local Institution - 0093, México

65653

Local Institution - 0156, Brno

66205

Local Institution - 0178, Westwood

68020

Local Institution - 0098, Oaxaca City

69310

Local Institution - 0041, Pierre-Bénite

72076

Local Institution - 0092, Tübingen

72762

Local Institution - 0164, Springdale

75010

Local Institution - 0042, Paris

75246

Local Institution - 0163, Dallas

77030

Local Institution - 0172, Houston

78731

Local Institution - 0146, Austin

80045

Local Institution - 0138, Aurora

80131

Local Institution - 0119, Napoli

80337

Local Institution - 0076, Munich

90025

Local Institution - 0200, Los Angeles

90404

Saint John's Cancer Institute, Santa Monica

91054

Local Institution - 0074, Erlangen

94115

Local Institution - 0162, San Francisco

94304

Local Institution - 0185, Palo Alto

94800

Local Institution - 0040, Villejuif

97080

Local Institution - 0080, Würzburg

100034

Local Institution - 0259, Beijing

100035

Local Institution - 0261, Beijing

100142

Local Institution - 0214, Beijing

110001

Local Institution - 0242, Shenyang

130021

Local Institution - 0219, Changchun

200542

Local Institution - 0066, Craiova

210000

Local Institution - 0215, Nanjing

210029

Local Institution - 0225, Nanjing

230022

Local Institution - 0221, Hefei

300060

Local Institution - 0263, Tianjin

310016

Local Institution - 0220, Hangzhou

310022

Local Institution - 0216, Hangzhou

330006

Local Institution - 0224, Nanchang

350014

Local Institution - 0245, Fuzhou

400015

Local Institution - 0065, Cluj-Napoca

400030

Local Institution - 0241, Chongqing

407280

Local Institution - 0064, Floresti/ Cluj

410013

Local Institution - 0234, Changsha Shi

430022

Local Institution - 0237, Wuhan

430030

Local Institution - 0239, Wuhan

450001

Local Institution - 0226, Zhengzhou

500283

Local Institution - 0170, Brasov

510060

Local Institution - 0217, Guangzhou

610041

Local Institution - 0230, Chengdu

650106

Local Institution - 0222, Kunming

830000

Local Institution - 0228, Ürümqi

1834111

Local Institution - 0116, Afula

4941492

Local Institution - 0199, Petah Tikva

5262100

Local Institution - 0117, Ramat Gan

7510032

Local Institution - 0013, Santiago

8420383

Local Institution - 0006, Santiago

9112001

Local Institution - 0118, Jerusalem

14784400

Local Institution - 0070, Barretos

29055450

Local Institution - 0068, Vitória

60135237

Local Institution - 0072, Fortaleza

02215

Dana-Farber Cancer Institute-Melanoma, Boston

07601

Local Institution - 0139, Hackensack

07960

Local Institution - 0206, Morristown

C1426ABP

Local Institution - 0003, Ciudad Autónoma de Buenos Aires

C1430

Local Institution - 0001, CABA

C1121ABE

Local Institution - 0002, Ciudad de Buenos Aires

X5002HWE

Local Institution - 0004, Córdoba

0810

Local Institution - 0254, Tiwi

40170-070

Local Institution - 0071, Salvador

30130-090

Local Institution - 0047, Belo Horizonte

98700-000

Local Institution - 0056, Ijuí

90035-903

Local Institution - 0257, Porto Alegre

91350-200

Local Institution - 0049, Porto Alegre

96830-180

Local Institution - 0048, Santa Cruz do Sul

20220-410

Local Institution - 0058, Rio de Janeiro

T6X 1E8

Local Institution - 0155, Edmonton

V5Z 4E6

Local Institution - 0175, Vancouver

B3H 2Y9

Local Institution - 0197, Halifax

H2X 1P1

Local Institution - 0159, Montreal

H3T 1E2

Local Institution - 0158, Montreal

G1J 1Z4

Local Institution - 0160, Québec

J1H 5N4

Local Institution - 0198, Sherbrooke

Unknown

Local Institution - 0014, Santiago

030032

Local Institution - 0244, Taiyuan

708 52

Local Institution - 0026, Ostrava

00290

Helsinki University Hospital Adult ICU PPDS, Helsinki

01307

Local Institution - 0077, Dresden

07548

Local Institution - 0081, Gera

D-69120

Local Institution - 0075, Heidelberg

185 47

Local Institution - 0113, Neo Faliro

540 07

Local Institution - 0112, Thessaloniki

06132

Local Institution - 0122, Perugia

03240

Local Institution - 0100, Benito Juárez

0310

Local Institution - 0017, Oslo

3000-075

Local Institution - 0249, Coimbra

06071

Local Institution - 0188, Badajoz

08035

Local Institution - 0201, Barcelona

221 85

Local Institution - 0011, Lund

171 64

Local Institution - 0012, Solna

NG5 1PB

Local Institution - 0101, Nottingham

BS2 8ED

Local Institution - 0102, Bristol

G12 0YN

Local Institution - 0187, Glasgow

NE7 7DN

Local Institution - 0154, Newcastle upon Tyne

OX3 7LE

Local Institution - 0232, Oxford

SO16 0YD

Local Institution - 0127, Southampton

Sponsors
All Listed Sponsors
lead

Bristol-Myers Squibb

INDUSTRY

NCT05002569 - A Study to Assess Adjuvant Immunotherapy With Nivolumab Plus Relatlimab Versus Nivolumab Alone After Complete Resection of Stage III-IV Melanoma | Biotech Hunter | Biotech Hunter