Chemotherapy With or Without Immunotherapy for Peritoneal Mesothelioma

PHASE2RecruitingINTERVENTIONAL
Enrollment

66

Participants

Timeline

Start Date

March 22, 2022

Primary Completion Date

August 20, 2026

Study Completion Date

August 20, 2026

Conditions
Peritoneal Malignant Mesothelioma
Interventions
BIOLOGICAL

Atezolizumab

Given IV

BIOLOGICAL

Bevacizumab

Given IV

PROCEDURE

Biospecimen Collection

Undergo blood and tissue sample collection

DRUG

Carboplatin

Given IV

PROCEDURE

Computed Tomography

Undergo CT scan

PROCEDURE

Cytoreductive Surgery

Undergo surgery

DRUG

Hyperthermic Intraperitoneal Chemotherapy

Undergo HIPEC

DRUG

Pemetrexed

Given IV

PROCEDURE

Positron Emission Tomography

Undergo PET scan

Trial Locations (39)

15232

RECRUITING

University of Pittsburgh Cancer Institute (UPCI), Pittsburgh

40536

ACTIVE_NOT_RECRUITING

University of Kentucky/Markey Cancer Center, Lexington

43210

RECRUITING

Ohio State University Comprehensive Cancer Center, Columbus

54449

RECRUITING

Marshfield Medical Center-Marshfield, Marshfield

54476

RECRUITING

Marshfield Medical Center - Weston, Weston

54482

RECRUITING

Marshfield Medical Center-River Region at Stevens Point, Stevens Point

54548

RECRUITING

Marshfield Medical Center - Minocqua, Minocqua

54701

RECRUITING

Marshfield Medical Center-EC Cancer Center, Eau Claire

54868

RECRUITING

Marshfield Medical Center-Rice Lake, Rice Lake

54911

RECRUITING

ThedaCare Regional Cancer Center, Appleton

55101

RECRUITING

Regions Hospital, Saint Paul

55102

RECRUITING

United Hospital, Saint Paul

55407

RECRUITING

Abbott-Northwestern Hospital, Minneapolis

55416

RECRUITING

Park Nicollet Clinic - Saint Louis Park, Saint Louis Park

55432

ACTIVE_NOT_RECRUITING

Unity Hospital, Fridley

55433

RECRUITING

Mercy Hospital, Coon Rapids

55435

RECRUITING

Fairview Southdale Hospital, Edina

55905

RECRUITING

Mayo Clinic in Rochester, Rochester

56187

SUSPENDED

Sanford Cancer Center Worthington, Worthington

56601

RECRUITING

Sanford Joe Lueken Cancer Center, Bemidji

57104

RECRUITING

Sanford Cancer Center Oncology Clinic, Sioux Falls

58122

RECRUITING

Sanford Broadway Medical Center, Fargo

RECRUITING

Sanford Roger Maris Cancer Center, Fargo

58501

RECRUITING

Sanford Bismarck Medical Center, Bismarck

60637

RECRUITING

University of Chicago Comprehensive Cancer Center, Chicago

61801

RECRUITING

Carle Cancer Center, Urbana

RECRUITING

The Carle Foundation Hospital, Urbana

61832

RECRUITING

Carle at The Riverfront, Danville

61938

RECRUITING

Carle Physician Group-Mattoon/Charleston, Mattoon

62401

RECRUITING

Carle Physician Group-Effingham, Effingham

73104

RECRUITING

University of Oklahoma Health Sciences Center, Oklahoma City

77030

RECRUITING

M D Anderson Cancer Center, Houston

77079

RECRUITING

MD Anderson West Houston, Houston

77384

RECRUITING

MD Anderson in The Woodlands, Conroe

77478

RECRUITING

MD Anderson in Sugar Land, Sugar Land

77573

RECRUITING

MD Anderson League City, League City

85054

SUSPENDED

Mayo Clinic Hospital in Arizona, Phoenix

02115

RECRUITING

Alliance for Clinical Trials in Oncology, Boston

57117-5134

RECRUITING

Sanford USD Medical Center - Sioux Falls, Sioux Falls

All Listed Sponsors
lead

National Cancer Institute (NCI)

NIH