Top Down Versus Step up in Pediatric Ulcerative Colitis

PHASE4RecruitingINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

November 1, 2021

Primary Completion Date

June 1, 2025

Study Completion Date

December 31, 2026

Conditions
Ulcerative ColitisInfliximabChildren
Interventions
DRUG

Infliximab

Infliximab will be administered intravenously at a dose of 5 mg/kg for 0, 2, and 6 weeks, then every 8 weeks for 1 year.

DRUG

Corticosteroids

Corticosteroid will be given at a dose of 1-2mg/kg/day (maximum 60 mg/kg/day),oral or intravenously for 12 to 14 weeks.

Trial Locations (1)

201102

RECRUITING

Children's Hospital of Fudan University, Shanghai

All Listed Sponsors
lead

Children's Hospital of Fudan University

OTHER