MPFC Theta Burst Stimulation as a Treatment Tool for Alcohol Use Disorder: Effects on Drinking and Incentive Salience

NARecruitingINTERVENTIONAL
Enrollment

86

Participants

Timeline

Start Date

July 6, 2021

Primary Completion Date

December 31, 2026

Study Completion Date

December 31, 2026

Conditions
Alcohol Use DisorderAlcohol DrinkingSubstance UseDrinking, AlcoholAlcohol Use Disorder (AUD)
Interventions
DEVICE

Real TBS to the mPFC

This will be delivered with the Magventure Magpro system; 600 pulses of continuous theta burst stimulation with the active sham coil (double blinded using the integrated active sham system).

DEVICE

Sham TBS to the mPFC

This will be delivered with the Magventure Magpro system; 600 pulses with the active sham coil (double blinded using the integrated active sham system). The MagVenture MagPro system has an integrated active sham that passes current through two surface electrodes placed on the scalp. The electrodes are placed on the left frontalis muscle under the coil for both the real and sham stimulation sessions.

Trial Locations (1)

29401

RECRUITING

Medical University of South Carolina, Charleston

All Listed Sponsors
collaborator

National Institutes of Health (NIH)

NIH

collaborator

National Institute on Alcohol Abuse and Alcoholism (NIAAA)

NIH

lead

Medical University of South Carolina

OTHER