Intrauterine Infusion of GCSF and Reproductive Outcomes in Infertile Women with History of RIF

CompletedOBSERVATIONAL
Enrollment

100

Participants

Timeline

Start Date

September 1, 2019

Primary Completion Date

August 30, 2024

Study Completion Date

September 25, 2024

Conditions
Recurrent Implantation FailureGranulocyte Colony-Stimulating FactorInfertility
Interventions
DRUG

Granulocyte Colony-Stimulating Factor

Granulocyte-colony stimulating factors (G-CSF) is synthesized in the reproductive tract naturally, it is a hematopoietic lineage-specific cytokine which is known for its specific effects on the activation of intracellular signaling pathways that are associated with the cell proliferation, differentiation, and stimulation of hematopoietic cells of the neutrophilic granulocyte lineage; which act on macrophages of decidual cells and finally affect implantation

OTHER

placebo

mock test without injection of G-CSF

Trial Locations (1)

Unknown

Cairo university Kasr Alainy OBGYN hospital, Cairo

All Listed Sponsors
lead

Cairo University

OTHER

NCT04998279 - Intrauterine Infusion of GCSF and Reproductive Outcomes in Infertile Women with History of RIF | Biotech Hunter | Biotech Hunter