NCT04998097View on ClinicalTrials.gov

The Role of iTBS in Bipolar II Depression

NARecruitingINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

May 23, 2022

Primary Completion Date

March 31, 2024

Study Completion Date

March 31, 2024

Conditions
Bipolar II Disorder, Most Recent Episode Major Depressive
Interventions
DEVICE

repetitive transcranial magnetic stimulation (rTMS)

Investigators adopted the iTBS protocol which follows the standard TBS protocols, with 3-pulse 50-Hz bursts given every 200 ms (at 5 Hz) and an intensity of 80% motor threshold. In each session, a 2-s train of bursts will be repeated every 10 s for a total of 570 s (1800 pulses) to the left dorsolateral prefrontal cortex (DLPFC). TBS sessions will be scheduled daily in a 5-day sequence, for a total of 10 sessions in 2 weeks.

DEVICE

sham repetitive transcranial magnetic stimulation (rTMS)

no stimulation, Sham TBS sessions will be scheduled daily in a 5-day sequence, for a total of 10 sessions in 2 weeks.

Trial Locations (1)

813

RECRUITING

KaohsiungVGH, Kaohsiung City

All Listed Sponsors
lead

Kaohsiung Veterans General Hospital.

OTHER