25,600
Participants
Start Date
July 26, 2021
Primary Completion Date
December 31, 2025
Study Completion Date
December 31, 2025
Assessment of Psychophysiological factors
Investigating the presence of psychophysiological factors (depression, anxiety, catastrophizing) by questionnaires.
Assessment of Biological factors
Investigating autonomic nervous function using heart rate recording, colon biopsy samples, microbiota, and blood cytokines levels. (Colon biopsy samples are obtained when colonoscopy is performed for clinical reasons. Blood samples and stool samples will be taken when participants come to the hospital for colonoscopy)
Assessment of Genetics
Genetic data investigated by another cohort study (IBD BioResource study) will be utilized in the analysis of this study.
Assessment of Quality of Life
Investigating QOL by questionnaires.
Assessment of Biological factors
Investigating colon biopsy samples (Colon biopsy samples are obtained when colonoscopy is performed for clinical reasons).
RECRUITING
Neurogastroenterology, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London
University of Birmingham
OTHER
University of Cambridge
OTHER
Barking, Havering and Redbridge University Hospitals NHS Trust
OTHER
Barts & The London NHS Trust
OTHER
University College London Hospitals
OTHER
Royal Free Hospital NHS Foundation Trust
OTHER
King's College London
OTHER
Queen Mary University of London
OTHER