Optimized Antiplatelet Therapy in Patients With CHD After Implantation of NeoVas™ BRS System

NANot yet recruitingINTERVENTIONAL
Enrollment

2,150

Participants

Timeline

Start Date

September 30, 2021

Primary Completion Date

January 31, 2026

Study Completion Date

January 31, 2028

Conditions
Coronary Heart Disease
Interventions
DRUG

Single anti-platelet therapy

Aspirin in combination with a P2Y12 receptor antagonist (either clopidogrel or ticagrelor will be selected by investigators according to the degree of ischemia) in the first year after PCI. Aspirin will be discontinued one year after surgery and clopidogrel will be continued until 5 years after surgery.

DRUG

Dual anti-platelet therapy

Aspirin in combination with a P2Y12 receptor antagonist (either clopidogrel or ticagrelor will be selected by investigators according to the degree of ischemia) in the first year after PCI. Patients continue to take dual antiplatelet (DAPT) drugs, including aspirin and clopidogrel, for 2 more years; then aspirin will be used alone from the 4th year to the 5th year.

Trial Locations (114)

100005

Peking Union Medical College Hospital, Beijing

100020

Beijing Chaoyang Hospital, Capital Medical University, Beijing

100029

Beijing Anzhen Hospital, Capital Medical University-12 Ward, Beijing

Beijing Anzhen Hospital, Capital Medical University-28 Ward, Beijing

Beijing Anzhen Hospital, Capital Medical University-33 Ward, Beijing

100038

Beijing Shijitan Hospital, Capital Medical University, Beijing

100050

Beijing Friendship Hospital, Capital Medical University, Beijing

100053

Xuan Wu Hospital, Capital Medical University, Beijing

100191

Peking University Third Hospital, Beijing

101199

Beijing Luhe Hospital, Capital Medical University, Beijing

102399

Beijing Jingmei Group General Hospital, Beijing

110016

The People's Hospital of Liaoning Province, Shenyang

110066

General Hospital of Northern Theater Command, Shenyang

116001

Affiliated Zhongshan Hospital of Dalian University, Dalian

116089

Dalian Municipal Central Hospital Affiliated of Dalian Medical University, Dalian

130033

China-Japan Union Hospital of Jilin University, Changchun

130041

The Second Hospital of Jilin University, Changchun

130061

The First Bethune Hospital of Jilin University, Changchun

150001

The Fourth Hospital of Harbin Medical University, Harbin

150086

The Second Hospital of Harbin Medical University, Harbin

200003

Shanghai Changzheng Hospital, Shanghai

200025

Ruijin Hospital Affiliated to School of Medicine, Shanghai Jiaotong University, Shanghai

200030

Shanghai Chest Hospital, Shanghai

200092

Xinhua Hospital Affiliated to School of Medicine, Shanghai Jiaotong University, Shanghai

200120

Shanghai East Hospital, Shanghai

200433

Changhai Hospital, Shanghai

200940

Shanghai General Hospital, Shanghai

201306

Shanghai 6th People's Hospital, Shanghai

210009

Zhongda Hospital Southeast University, Nanjing

210029

The First Affiliated Hospital with Nanjing Medical University, Nanjing

221005

Xuzhou Cancer Hospital, Xuzhou

221006

The Affiliated Hospital of Xuzhou Medical University, Xuzhou

222000

Affiliated Lianyungang Hospital of Nanjing University of Chinese Medicine, Lianyungang

223300

Gynecology of Huai'an First People's Hospital, Nanjing Medical University, Huai'an

230022

The First Affiliated Hospital with Anhui Medical University, Hefei

233099

The First Affiliated Hospital of Bengbu Medical College, Bengbu

241001

The First Affiliated Hospital of Wannan Medical College, Wuhu

250012

Qilu Hospital of Shandong University, Jinan

255020

Zibo Central Hospital, Zibo

264099

Yantai Yuhuangding Hospital, Yantai

264400

Weihai Central Hospital, Weihai

266000

The Affiliated Hospital of Qingdao University, Qingdao

300222

Tianjin Chest Hospital, Tianjin

300457

Teda International Cardiovascular Hospital, Tianjin

310016

Sir Run Run Shaw Hospital, Zhejiang University, Hangzhou

311100

The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou

330006

Jiangxi Provincial People's Hospital, Nanchang

The First Affiliated Hospital of Nanchang University, Nanchang

The Second Affiliated Hospital of Nanchang University, Nanchang

335000

Yingtan People's Hospital, Yingtan

341000

The First Affiliated Hospital of Gannan Medical College, Ganzhou

400042

The First Affiliated Hospital of Chongqing Medical University, Chongqing

The Second Affiliated Hospital of Chongqing Medical University, Chongqing

410008

Xiangya Hospital, Central South University, Changsha

411199

Xiangtan Central Hospital, Xiangtan

430022

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan

430050

Fifth Hospital in Wuhan, Wuhan

430060

Renmin Hospital of Wuhan University, Wuhan

430071

Zhongnan Hospital of Wuhan University, Wuhan

434020

Jingzhou Central Hospital, Jingzhou

450001

Zhengzhou Central Hospital, Zhengzhou

450003

Henan Provincial People's Hospital, Zhengzhou

450008

Henan Provincial Chest Hospital, Zhengzhou

450014

The Second Affiliated Hospital, Zhengzhou University, Zhengzhou

450016

The 7th People's Hospital of Zhengzhou, Zhengzhou

450052

The First Affiliated Hospital of Henan University of Science and Technology, Zhengzhou

The First Affiliated Hospital, Zhengzhou University, Zhengzhou

450099

The First Affiliated Hospital of Henan University of Chinese Medicine, Zhengzhou

451460

Fuwai Central China Cardiovascular Hospital, Zhengzhou

453099

Xinxiang Central Hospital, Xinxiang

453199

The First Affiliated Hospital of Xinxiang Medical University, Xinxiang

473005

Nanyang Central Hospital, Nanyang

473009

Nanyang Second General Hospital, Nanyang

510000

Guangdong Provincial Hospital of Traditional Chinese Medicine, Guangzhou

510150

The Third Affiliated Hospital of Guangdong Medical University, Guangzhou

515041

Shantou Central Hospital, Shantou

The First Affiliated Hospital of Shantou University Medical College, Shantou

The Second Affiliated Hospital of Shantou University Medical College, Shantou

518055

Shenzhen University General Hospital, Shenzhen

519000

The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai

524000

Zhanjiang Central People's Hospital, Zhanjiang

528000

Foshan First People's Hospital, Foshan

530021

The First Affiliated Hospital of Guangxi Medical University, Nanning

530022

The First People's Hospital of Nanning, Nanning

537099

Yulin First People's Hospital, Yulin

541002

Guilin People's Hospital, Guilin

545006

Liuzhou People's Hospital, Liuzhou

Liuzhou Worker's Hospital, Liuzhou

550000

Guizhou Provincial People's Hospital, Guiyang

570208

Haikou People's Hospital, Haikou

570216

The Second Affiliated Hospital of Hainan Medical University, Haikou

571199

Sanya Central Hospital (Hainan Third People's Hospital), Sanya

650000

Fuwai Yunnan Cardiovascular Hospital, Kunming

650034

The First People's Hospital of Yunnan, Kunming

710004

The Second Affiliated Hospital of Xi'an Jiaotong University, Xi’an

710032

First Affiliated Hospital of the Fourth Military Medical University, Xi’an

710061

The First Affiliated Hospital of Xi'an Jiaotong University, Xi’an

710068

Shanxi Provincial Hospital, Xi’an

716000

Tangdu Hospital of the Fourth Military Medical University of the PLA, Yanan

Yan'an University Affiliated Hospital, Yanan

721008

Baoji Central Hospital, Baoji

730000

Gansu Provincial Hospital, Lanzhou

The First Hospital of Lanzhou University, Lanzhou

730099

Lanzhou University Second Hospital, Lanzhou

750003

General Hospital of Ningxia Medical University, Yinchuan

830001

People's Hospital of Xinjiang Uygur Autonomous Region, Ürümqi

061011

Cangzhou Central Hospital, Cangzhou

053099

Hengshui People's Hospital, Hengshui

050057

Hebei General Hospital, Shijiazhuang

050082

the 980th Hospital of Chinese People's Liberation Army Joint Logistics Support Force, Shijiazhuang

054001

Xingtai People's Hospital, Xingtai

014017

The First Affiliated Hospital of Baotou Medical College, Inner Mongolia University of Science, Baotou

030001

Second Hospital of Shanxi Medical University, Taiyuan

030024

Shanxi Cardiovascular Hospital, Taiyuan

All Listed Sponsors
lead

Lepu Medical Technology (Beijing) Co., Ltd.

INDUSTRY