Impact of Chemotherapy on Urinary Biomarkers and Non-Invasive Urodynamics in Children

RecruitingOBSERVATIONAL
Enrollment

152

Participants

Timeline

Start Date

June 2, 2021

Primary Completion Date

July 9, 2026

Study Completion Date

July 9, 2026

Conditions
Survivors of Childhood CancerBladder Dysfunction
Interventions
DIAGNOSTIC_TEST

Non-invasive Urodynamic Test (niUDS)

A noninvasive urodynamics is a simple test used to evaluate urinary flow.

DIAGNOSTIC_TEST

Urinary proteomic screen

Urine proteomics is a powerful platform to identify urinary excreted proteins and peptides in different stages of disease or therapy and to determine their quantity, functions, and interaction.

OTHER

Dysfunctional Voiding Symptom Score Survey (DVSS)

The Dysfunctional Voiding Symptom Score provides accurate and objective grading of voiding behaviors of children.

Trial Locations (1)

80045

RECRUITING

Children's Hospital Colorado, Aurora

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

collaborator

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NIH

collaborator

Children's Hospital Colorado

OTHER

lead

University of Colorado, Denver

OTHER