Mechanism of Action of Transcranial Direct Current Stimulation in Neurofibromatosis Type 1

NACompletedINTERVENTIONAL
Enrollment

31

Participants

Timeline

Start Date

February 22, 2019

Primary Completion Date

February 19, 2020

Study Completion Date

February 19, 2020

Conditions
Neurofibromatosis 1
Interventions
OTHER

Transcranial direct current stimulation

tDCS is a form of non-invasive brain stimulation. tDCS is an established research tool for non-invasive modulation of neuroplasticity. It uses low-intensity DC currents to modulate spontaneous neuronal network activity by altering the resting membrane potential. Anodal tDCS has been shown to increase cortical excitability, reduce regional levels of GABA enhance LTP and synaptic plasticity.

Trial Locations (1)

M13 9QQ

University of Manchester, Manchester

All Listed Sponsors
lead

University of Manchester

OTHER

NCT04991428 - Mechanism of Action of Transcranial Direct Current Stimulation in Neurofibromatosis Type 1 | Biotech Hunter | Biotech Hunter