Microvascular Injury and Distal Thrombosis in COVID-19

CompletedOBSERVATIONAL
Enrollment

25

Participants

Timeline

Start Date

February 22, 2020

Primary Completion Date

October 18, 2021

Study Completion Date

February 28, 2022

Conditions
SARS-CoV-2 Infection
Interventions
DIAGNOSTIC_TEST

lung ventilation/perfusion scintigraphy

"Chest CT-scan will be performed with blocked inspiration.~Lung ventilation/perfusion scintigraphy imaging will be performed within 24hrs after CT pulmonary angiography, 410MBq of Technegas will be inhaled by patients and ventilation tomography performed thereafter. Then, 185MBq 99mTc-macroaggegates will be injected intravenously followed by the perfusion tomography.~A combined CT acquisition will be performed.~The day following lung ventilation/perfusion scintigraphy, 740MBq of Tc99m labeled albumin will be intravenously administered.~Cardiac gated-blood-pool scintigraphy will be then performed in best septal left anterior oblique and left profile according to specific parameters.~45-60 min after injection, a non-gated tomographic acquisition over the lungs will be done, with the same parameters than for PS SPECT, resulting in a late albumin acquisition."

Trial Locations (1)

Unknown

Centre Hospitalier Princesse Grace, Monaco

All Listed Sponsors
lead

Centre Hospitalier Princesse Grace

OTHER

NCT04990505 - Microvascular Injury and Distal Thrombosis in COVID-19 | Biotech Hunter | Biotech Hunter