Comparison The Postoperative Effects of Local and Systemic Antibiotics Applied With Platelets Rich Fibrin

CompletedOBSERVATIONAL
Enrollment

75

Participants

Timeline

Start Date

March 17, 2019

Primary Completion Date

February 20, 2021

Study Completion Date

February 21, 2021

Conditions
Impacted Wisdom Tooth
Interventions
DIAGNOSTIC_TEST

Diagnosis

All of the patients withstand a radiological examination, including panoramic radiography, and all were handled by the same surgeon and assistant.

PROCEDURE

traditional osteotomies

In all groups the flap incision was triangular in shape which avoids muscle involvement (Archer flap).

BIOLOGICAL

Platelet Rich Fibrin

Platelet rich fibrin (PRF), is an example and popular procedure for accelerate healing of soft and hard tissue because of the presence of various growth factors.a blood sample was taken without anticoagulant in 10 mL glass-coated plastic tubes that were immediately centrifuged (Elektro-mag M415P) at 3,000 rpm for 10 min (approximately 400 g) (13). The platelet-poor plasma that accumulated at the top of the tubes was discarded.PRF was dissected approximately 2 mm below its contact point with the red corpuscles situated beneath, to include any remaining platelets that may have localized below the junction between the PRF and red corpuscles.

DRUG

Antibiotics, Penicillin

Antibiotics are prescribed for the patients.

DRUG

Analgesic

Analgesics are prescribed for the patients.

DRUG

Antibiotic

Patients with penicillin allergy

Trial Locations (1)

99138

Near east University, Nicosia

All Listed Sponsors
lead

Ceren Melahat Donmezer

OTHER

NCT04989127 - Comparison The Postoperative Effects of Local and Systemic Antibiotics Applied With Platelets Rich Fibrin | Biotech Hunter | Biotech Hunter