The Impact of Sildenafil on the Pulmonary Circulation in Healthy Trained and Untrained Humans

Sildenafil is a phosphodiesterase type-5 inhibitor, which augments/prolongs the naturally occurring nitric oxide mediated vasodilatory pathway. Sildenafil pill is over-encapsulated to be identical in appearance to the placebo intervention.

Medical-grade placebo pill, over-encapsulated to be identical in appearance to the sildenafil intervention.