Individualized Diagnosis and Treatment of Extraesophageal Reflux in Patients With Chronic Cough

NARecruitingINTERVENTIONAL
Enrollment

150

Participants

Timeline

Start Date

June 1, 2021

Primary Completion Date

May 31, 2024

Study Completion Date

May 31, 2024

Conditions
Chronic CoughExtraesophageal RefluxLaryngopharyngeal RefluxAllergyAsthma
Interventions
BEHAVIORAL

Lifestyle modifications and Antireflux diet

Patients in Arm 1 - mild cough only slightly worsening the quality of life (VAS 1-3) will undergo treatment using lifestyle modifications and an Antireflux diet for 3 months.

DIAGNOSTIC_TEST

Extraesophageal reflux diagnostic

Patients in Arm 2 - moderate and severe cough that significantly worsen the quality of life (VAS 4-10) will undergo extraesophageal reflux diagnostics consisting of esophageal 24-hour pH/Impedance Reflux Monitoring and peptest study on fasting

Trial Locations (1)

70852

RECRUITING

University Hospital Ostrava, Ostrava

All Listed Sponsors
lead

University Hospital Ostrava

OTHER