A Study to Evaluate the Effect of Multiple Doses of Itraconazole, Phenytoin, and Paroxetine on the Single-Dose Pharmacokinetics of Poziotinib in Healthy Adult Participants

PHASE1CompletedINTERVENTIONAL

Enrollment

Participants

Timeline

Start Date

April 8, 2021

Primary Completion Date

June 30, 2021

Study Completion Date

August 17, 2021

Conditions

Healthy

Interventions

DRUG

Poziotinib

Poziotinib Tablets

DRUG

Itraconazole

Itraconazole Oral solution

DRUG

Phenytoin

Phenytoin Capsules

DRUG

Paroxetine

Paroxetine Tablets

Trial Locations (1)

Celerion, Phoenix clinical facility, Tempe

All Listed Sponsors

lead

Spectrum Pharmaceuticals, Inc

INDUSTRY