Safety of Anticoagulant Therapy After Endoscopic Treatment

PHASE4CompletedINTERVENTIONAL
Enrollment

86

Participants

Timeline

Start Date

February 1, 2020

Primary Completion Date

December 31, 2021

Study Completion Date

June 28, 2022

Conditions
CirrhosisPortal Vein ThrombosisEsophageal and Gastric VaricesAnticoagulant-induced Bleeding
Interventions
DRUG

nadroparin calcium-warfarin sequential anticoagulation

The NWS therapy group were given a subcutaneous injection of nadroparin calcium every 12 hours for 1 month and switched to warfarin for 5 months. Warfarin was initiated at least 5 days before nadroparin calcium was stopped. International normalized ratio (INR) was detected every 3-4 days and adjusted carefully by 0.75mg dosage until achieve the target level of 2-3.

Trial Locations (1)

250012

Department of Gastroenterology,Qilu Hospital,Shandong University, Jinan

All Listed Sponsors
collaborator

Liaocheng People's Hospital

OTHER

collaborator

Taian City Central Hospital

OTHER

lead

Qilu Hospital of Shandong University

OTHER

NCT04976543 - Safety of Anticoagulant Therapy After Endoscopic Treatment | Biotech Hunter | Biotech Hunter