Adjunct Targeted Temperature Management in Acute Severe Carbon Monoxide Poisoning

NAActive, not recruitingINTERVENTIONAL
Enrollment

46

Participants

Timeline

Start Date

October 25, 2021

Primary Completion Date

December 31, 2025

Study Completion Date

December 31, 2025

Conditions
Carbon Monoxide PoisoningNeurologic SequelaeHypothermia
Interventions
OTHER

Targeted therapeutic hypothermia

Targeted therapeutic hypothermia is then performed at a body temperature of 33±0.5 °C during 24 h using a surface cooling device as soon as possible after the HBO and research consent. After TH ended, rewarming is done slowly between 0.2℃ - 0.5℃/h for 12 hours. After rewarming, it will be held at 36.5 ℃ for 36 hours.

OTHER

Targeted therapeutic normothermia

Targeted therapeutic normothermia will be held at 36.5±0.5 ℃ for 72 hours using a surface cooling device after the HBO and research consent.

Trial Locations (2)

22332

Inha University Hospital, Incheon

26426

Wonju Severance Christian Hospital, Wŏnju

All Listed Sponsors
collaborator

National Research Foundation of Korea

OTHER

lead

Wonju Severance Christian Hospital

OTHER