Effect of Electro-acupuncture on Women With Diminished Ovarian Reserve

NARecruitingINTERVENTIONAL
Enrollment

338

Participants

Timeline

Start Date

September 9, 2019

Primary Completion Date

December 31, 2024

Study Completion Date

December 31, 2025

Conditions
Diminished Ovarian Reserve
Interventions
OTHER

Treatment group protocol

"For treatment group, two groups of acupoints will be used alternatively. The first group consists of some acupoints. The patients will be asked to stay in supine position. Disposable sterilized needles (Size: 0.25\*40/50 mm) will be inserted into a depth of 15\~35 mm and stimulated manually to evoke needle sensation. And then some acupoints will be thereafter connected to electrical stimulators and stimulated with low-frequency and the maximum tolerated intensity of the patients. The other needles without electrical stimulators will be manually stimulated to evoke Deqi every 10 minutes.~The second group consists of other acupoints. Patients will be asked to stay in prone position. The stimulation will be in the same way as the first group."

OTHER

Control group protocol

"For control group, four pseudo-acupoints are used, with two points on each shoulder and the two on each upper arm, which are not located on any meridians. The patients will be asked to stay in supine position and keep the whole body relaxed and comfortable. Disposable sterilized needles (Size: 0.18\*25 mm) will be inserted superficially to a depth of \< 5 mm without any manual stimulus and the needle sensation (Deqi in TCM) should not be evoked. Electrodes are connected to the needles, but the stimulators should be turned on at an intensity of zero. Each intervention lasts for 30 minutes."

Trial Locations (1)

027

RECRUITING

Department of Integrated Traditional Chinese and Western Medicine Tongji hospital of Huazhong University of Science and Technology, Wuhan

Sponsors
All Listed Sponsors
collaborator

Wuhan No.1 Hospital

OTHER

collaborator

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

OTHER

collaborator

The Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine

OTHER

collaborator

Edwatz Medical Research Institude

UNKNOWN

collaborator

Wuhan Jinxin Gynecology and Obstetrics Hospital of Integrative Medicine

UNKNOWN

lead

Huazhong University of Science and Technology

OTHER