UW Withdraw From Tobacco Study

PHASE2CompletedINTERVENTIONAL
Enrollment

232

Participants

Timeline

Start Date

July 13, 2021

Primary Completion Date

September 21, 2022

Study Completion Date

September 21, 2022

Conditions
Tobacco Dependence
Interventions
DRUG

Combination nicotine replacement therapy (Nicotine patch + nicotine mini-lozenge)

Nicotine patch and mini-lozenge dosing will be based off the 2008 Public Health Services (PHS) Clinical Practice Guideline and package insert with adjustments to account for the delayed start 1-week post-TQD. All participants will receive 2mg mini-lozenge due to the superior palatability of the 2mg lozenges. Participants are encouraged to use at least 5 mini-lozenges per day for the full 8 weeks. Participants who report any smoking or nicotine use (e.g., even a cigarette puff, e-cigarette use) in the 3 days before C-NRT distribution will receive 4 weeks of 14mg and 4 weeks of 7mg nicotine patches. Participants who report complete abstinence from smoking and nicotine in the 3 days before C-NRT distribution will receive 8 weeks of 7mg nicotine patches.

Trial Locations (1)

53711

Center for Tobacco Research and Intervention, Madison

All Listed Sponsors
lead

University of Wisconsin, Madison

OTHER

collaborator

National Heart, Lung, and Blood Institute (NHLBI)

NIH