Accelerated Neuromodulation to Alleviate Cognitive Deficits Due to Cancer Therapy

NAActive, not recruitingINTERVENTIONAL
Enrollment

15

Participants

Timeline

Start Date

June 1, 2021

Primary Completion Date

July 18, 2023

Study Completion Date

January 21, 2026

Conditions
Cancer
Interventions
OTHER

Accelerated repetitive intermittent theta-burst transcranial stimulation (iTBS)

"Accelerated iTBS will be used to stimulate the regions of interest of mPFC and L-DLPFC nodes in cancer survivors or patients.~Accelerated iTBS will be administered in a single half-day period to allow for a 50minutes interval between any two treatments to minimize interference effects between treatments. Thus, there will be \~10 minute sessions of stimulation x 2 applications per node x 2 nodes (L-DLPFC, mPFC) = 40 total minutes of daily stimulation - each session delivers 1800 pulses in a 5 Hz triplet burst frequency, 2 second trains with intertrain interval of 8 seconds; triplets occur with 50 Hz frequency, as per standard iTBS protocols for depression treatment. The treatment will be offered for five consecutive days."

Trial Locations (1)

52242

University of Iowa Hospitals & Clinics, Iowa City

All Listed Sponsors
collaborator

American Cancer Society-Holden Comprehensive Cancer Society

UNKNOWN

collaborator

Fraternal Order of Eagles (Iowa)

UNKNOWN

lead

Sneha Phadke

OTHER