Tislelizumab Combined With Anlotinib and Chemotherapy (XELOX) in the Treatment of Advanced Gastric or Gastroesophageal Junction Adenocarcinoma (TALENT)

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

65

Participants

Timeline

Start Date

March 6, 2021

Primary Completion Date

March 15, 2024

Study Completion Date

March 20, 2024

Conditions
Gastric Cancer
Interventions
DRUG

BGB-A317

Subjects will be treated with BGB A317 200 mg IV on Day 1 during each 21-day cycle. BGB A317 will be administered until disease progression, intolerable toxicity, or treatment discontinuation for any other reason

DRUG

Anlotinib

oral administration daily d1-d14, q3w;

DRUG

Oxaliplatin

30 mg/m² IV on Day 1 during each 21-day cycle. during each 21-day cycle

DRUG

Capecitabine

1000 mg/m² orally twice daily (bid) Days 1 through 14 (14 days total) during each 21-day cycle. Capecitabine will be administered until disease progression, intolerable toxicity, or treatment discontinuation for any other reason.

Trial Locations (1)

Unknown

The First Affiliated Hospital with Nanjing Medical University, Nanjing

All Listed Sponsors
lead

The First Affiliated Hospital with Nanjing Medical University

OTHER

NCT04963088 - Tislelizumab Combined With Anlotinib and Chemotherapy (XELOX) in the Treatment of Advanced Gastric or Gastroesophageal Junction Adenocarcinoma (TALENT) | Biotech Hunter | Biotech Hunter