Timing of Endoscopy for Acute Variceal Bleeding in Patients With Cirrhosis

CompletedOBSERVATIONAL
Enrollment

3,300

Participants

Timeline

Start Date

December 16, 2019

Primary Completion Date

December 16, 2019

Study Completion Date

June 2, 2020

Conditions
Cirrhosis, LiverPortal HypertensionVarice Bleed
Interventions
DEVICE

emergency endoscopic therapy

When cirrhotic patients presented with AVB to the emergency department, emergency physicians consulted gastroenterologists on duty to assess the patient for suitability for endoscopy, usually after initial stabilization. Performance of endoscopy and its timing was at the discretion of the gastroenterologist on call. Therapeutic endoscopy for AVB was performed within 24 hours after consultation by an experienced attending endoscopist, using standard forward-viewing upper gastrointestinal video endoscopes at individual centers. Written informed consent for endoscopy was obtained before each procedure. The standard of care at all hospitals was to administer a vasoactive agent and antibiotics upon the patient's presentation. Packed red blood cells were transfused at the discretion of the attending gastroenterologist.

Trial Locations (1)

Unknown

The first hospital of Lanzhou university, Lanzhou

All Listed Sponsors
collaborator

LanZhou University

OTHER

collaborator

Beijing Shijitan Hospital, Capital Medical University

OTHER

collaborator

Beijing 302 Hospital

OTHER

collaborator

Tianjin Third Central Hospital

OTHER

collaborator

The Sixth People's Hospital of Shenyang

OTHER

collaborator

Shanxi Bethune Hospital

OTHER

collaborator

Linyi People's Hospital

OTHER

collaborator

Sir Run Run Shaw Hospital

OTHER

lead

Hepatopancreatobiliary Surgery Institute of Gansu Province

OTHER

NCT04957875 - Timing of Endoscopy for Acute Variceal Bleeding in Patients With Cirrhosis | Biotech Hunter | Biotech Hunter