Studies to Determine Whether Oxygen Sensing is Impaired in Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infected Patients

NACompletedINTERVENTIONAL
Enrollment

80

Participants

Timeline

Start Date

June 29, 2020

Primary Completion Date

April 21, 2022

Study Completion Date

April 21, 2022

Conditions
HypoxiaSARS-CoV-2 Acute Respiratory DiseaseCarotid Bodies
Interventions
DIAGNOSTIC_TEST

Phase-1: Breath Holding Test

In this phase of the study, each subject will be asked to hold their breath for up to 60 seconds or until they can longer hold it. While they are holding their breath, subjects will be hooked up to a monitor that will measure their Peripheral oxygen saturation (SpO2) respiratory rate (RR), and heart rate (HR).

DIAGNOSTIC_TEST

Phase 2: 6-Minute Walk Test (6MWT)

In this phase of the study, each subject will be asked to walk for 6 minutes in their hospital room or hallway. Their rate of perceived exertion will be measured while also hooked up to a monitor that will measure their Peripheral oxygen saturation (SpO2) respiratory rate (RR), and heart rate (HR).

Trial Locations (1)

60637

University of Chicago Medical Center, Chicago

All Listed Sponsors
lead

University of Chicago

OTHER

NCT04954157 - Studies to Determine Whether Oxygen Sensing is Impaired in Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infected Patients | Biotech Hunter | Biotech Hunter