NCT04948749View on ClinicalTrials.gov

Drug Eluting Stenting and Aggressive Medical Treatment for Preventing Recurrent Stroke in Intracranial Atherosclerotic Disease Trial

NARecruitingINTERVENTIONAL
Enrollment

792

Participants

Timeline

Start Date

July 2, 2021

Primary Completion Date

December 31, 2026

Study Completion Date

December 31, 2026

Conditions
ICAD - Intracranial Atherosclerotic DiseaseICAS - Intracranial AtherosclerosisDrug-eluting StentStrokeDrug Eluting Stents (DES)Medical Treatment
Interventions
DEVICE

Drug Eluting Stent implantation

The Maurora ® Sirolimus Eluting Stent System for intracranial PTA treatment comprises of a balloon expandable sirolimus eluting stent and a delivery catheter that features a rapid exchange catheter design with a semi-compliant balloon located at its distal end.

DRUG

Aggressive medical treatment

Aggressive medical treatment consists of dual antiplatelet treatment (aspirin 100 mg per day for the entire follow-up, clopidogrel 75 per day mg, or ticagrelor 90 mg twice per day for 6 months after enrollment).

BEHAVIORAL

Risk factor management

Management of risk factors (hypertension, diabetes, lipoprotein metabolism disorder, smoking and exercise)

DRUG

Standard medical treatment

Standard medical treatment consists of dual antiplatelet treatment (aspirin 100 mg per day for the entire follow-up, clopidogrel 75 per day mg, or ticagrelor 90 mg twice per day for 3 months after enrollment).

Trial Locations (18)

100070

RECRUITING

Beijing Tiantan Hospital, Beijing

Unknown

RECRUITING

Beijing Daxing District People's Hospital, Beijing

RECRUITING

Hejian People's Hospital, Cangzhou

RECRUITING

North China University of Science and Technology Affiliated Hospital, Tangshan

RECRUITING

Xingtai City Third Hospital, Xingtai

RECRUITING

General Hospital of The Yangtze River Shipping, Wuhan

RECRUITING

Baotou Central Hospital, Baotou

RECRUITING

Inner Mongolia Autonomous Region People's Hospital, Hohhot

RECRUITING

Tongliao City Hospital, Tongliao

RECRUITING

Wuhai People's Hospital, Wuhai

RECRUITING

The Second Affiliated Hospital of Nanjing Medical University, Nanjing

RECRUITING

The Second Norman Bethune Hospital of JilinUniversity,, Changchun

RECRUITING

General Hospital of Benxi Iron and Steel Co, Benxi

RECRUITING

Shanxi Cardiovascular Hospital, Taiyuan

RECRUITING

Shanxi Provincial People's Hospital, Taiyuan

RECRUITING

The First Affiliated Hospital of College of Medicine, Hangzhou

RECRUITING

Lishui People's Hospital, Lishui

RECRUITING

Beilun People's Hospital of Ningbo City, Ningbo

All Listed Sponsors
lead

Beijing Tiantan Hospital

OTHER