Sepsis in Geriatric Patients With Suspected Infection.

CompletedOBSERVATIONAL
Enrollment

580

Participants

Timeline

Start Date

April 1, 2019

Primary Completion Date

October 31, 2019

Study Completion Date

October 31, 2019

Conditions
Sepsis
Interventions
DIAGNOSTIC_TEST

Quick Sequential Organ Failure Assessment (qSOFA)

Clinical bedside tool that evaluates three vital parameters, scoring one point each if altered: respiratory rate (RR) ≥22 breaths/minute, systolic blood pressure (SBP) ≤100 mmHg and altered mental status (defined in our study as either Glasgow Coma Scale (GCS) score \<15 or any worsening in the Italian Oriented, Disoriented, Agitated, Sleepy scale). A qSOFA score ≥2 points is considered indicative of sepsis.

DIAGNOSTIC_TEST

Modified Early Warning Score (MEWS)

Clinical bedside tool that evaluates five vital parameters, with multiple scoring according to alteration: respiratory rate (0-3 points), heart rate (0-3 points), systolic blood pressure (0-3 points), body temperature (0-2 points), mental status (0-3 points, evaluated using the Alert, Verbal, Pain, Unresponsive - AVPU scale). A MEWS score ≥5 points is considered indicative of an acute condition at risk of sudden clinical deterioration.

DIAGNOSTIC_TEST

National Early Warning Score (NEWS)

Clinical bedside tool that evaluates seven parameters, with multiple scoring according to alteration: respiratory rate (0-3 points), oxygen saturation (0-3 points), need for any supplemental oxygen (0-2 points), body temperature (0-3 points), heart rate (0-3 points), systolic blood pressure (0-3 points), mental status (0-3 points, evaluated using the Alert, Verbal, Pain, Unresponsive - AVPU scale). A NEWS score ≥7 points is considered indicative of an acute condition at risk of sudden clinical deterioration.

Trial Locations (1)

10128

S.C. Geriatria U, A.O.U. Città della Salute e della Scienza di Torino, Turin

All Listed Sponsors
lead

A.O.U. Città della Salute e della Scienza

OTHER

NCT04945889 - Sepsis in Geriatric Patients With Suspected Infection. | Biotech Hunter | Biotech Hunter