NCT04938908View on ClinicalTrials.gov

Probiotic in Dry Eye Syndromes

PHASE2CompletedINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

July 1, 2021

Primary Completion Date

June 30, 2022

Study Completion Date

July 30, 2022

Conditions
Dry Eye Syndrome
Interventions
DRUG

Ophthalmic Probiotic

Bacterial lysate of Lactobacillus sakei, hydroxypropylmethylcellulose (HPMC), boric acid, sodium chloride, purified water.

DRUG

Opthalmic Placebo

Placebo contains complete formulation of the active drug except for bacterial lysate of Lactobacillus sakei (i.e. HPMC, boric acid, sodium chloride, purified water)

DIETARY_SUPPLEMENT

Oral Probiotic Capsule

Live Lactobacillus sakei (5 billion cfus) in hydroxypropylmethylcellulose hard capsule, with maltodextrin excipient

DIETARY_SUPPLEMENT

Oral Placebo Capsule

Hydroxypropylmethylcellulose hard capsule, filled with maltodextrin excipient

Trial Locations (1)

Unknown

Research Center for Traditional Medicine and History of Medicine-Shiraz University of Medical Sciences, Shiraz

All Listed Sponsors
lead

Shiraz University of Medical Sciences

OTHER