Segmentectomy Versus Lobectomy for Lung Adenocarcinoma ≤ 2cm

NARecruitingINTERVENTIONAL
Enrollment

690

Participants

Timeline

Start Date

October 1, 2019

Primary Completion Date

December 30, 2028

Study Completion Date

December 30, 2028

Conditions
Lung Adenocarcinoma
Interventions
PROCEDURE

Segmentectomy with systemic lymph node dissection

Segmentectomy with hilar and mediastinal lymph node dissection is performed. If the tumor located at inter-segment plane and without sufficient resection margin distance, a combined segmentectomy will be performed. Systemic or selective lymph node dissection is mandatory, and nodal sampling is not allowed. At least three stations of mediastinal lymph node from 2R, 4R, 7, 8, 9 for the right side and 5, 6, 7, 8, 9 for the left side, respectively. The distance from the dissection margin to the tumor edge must be evaluated intra-operatively. If the distance is either less than the maximum tumor diameter or 20 mm, the absence of cancer cells in the resection margin must be histologically or cytologically confirmed before finishing surgery.

PROCEDURE

Lobectomy with hilar and mediastinal lymph node dissection

Lobectomy with hilar and mediastinal lymph node dissection is performed. Segmentectomy with hilar and mediastinal lymph node dissection is performed. Systemic or selective lymph node dissection is mandatory, and nodal sampling is not allowed. At least three stations of mediastinal lymph node from 2R, 4R, 7, 8, 9 for the right side and 5, 6, 7, 8, 9 for the left side, respectively. The distance from the dissection margin to the tumor edge must be evaluated intra-operatively. If the distance is either less than the maximum tumor diameter or 20 mm, the absence of cancer cells in the resection margin must be histologically or cytologically confirmed before finishing surgery.

Trial Locations (14)

200433

RECRUITING

Shanghai Pulmonary Hospital, Shanghai

216002

RECRUITING

The Sixth People's Hospital of Nantong, Nantong

226001

RECRUITING

Affiliated Hospital of Nantong University, Nantong

310009

RECRUITING

The Second Affiliated Hospital Zhejiang University School of Medicine, Hangzhou

Unknown

RECRUITING

Anhui Chest Hospital, Hefei

RECRUITING

The First Affiliated Hospital of University of Science and Technology of China, Hefei

RECRUITING

Nanyang Central Hospital, Nanyang

RECRUITING

Affiliated Hospital of Xuzhou Medical University, Xuzhou

RECRUITING

Yancheng First People's Hospital, Yancheng

RECRUITING

Shandong Public Health Clinical Center, Jinan

RECRUITING

Huadong Hospital, Shanghai

RECRUITING

Huzhou Central Hospital, Huzhou

RECRUITING

Ningbo First Hospital, Ningbo

RECRUITING

Ningbo No.2 Hospital, Ningbo

All Listed Sponsors
lead

Shanghai Pulmonary Hospital, Shanghai, China

OTHER