Sirolimus vs Corticosteroids in Treatment of Thyroid Eye Disease

PHASE2RecruitingINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

January 1, 2023

Primary Completion Date

January 31, 2028

Study Completion Date

December 31, 2028

Conditions
Thyroid-Associated Ophthalmopathy
Interventions
DRUG

Sirolimus 1 mg Oral Tablet

2 mg Sirolimus (two 1 mg tablets) on the first day, followed by 0,5 mg Sirolimus (half 1 mg tablet) per day for 12 weeks.

DRUG

Methylprednisolone

500 mg Methylprednisolone intravenously once a week for 6 weeks, followed by 250 mg once a week for 6 weeks. Total period of treatment 12 weeks.

Trial Locations (1)

5021

RECRUITING

Department of Ophthalmology Haukeland University Hospital, Bergen

All Listed Sponsors
lead

Haukeland University Hospital

OTHER