1,158
Participants
Start Date
June 28, 2021
Primary Completion Date
January 30, 2027
Study Completion Date
July 31, 2027
Personalized hydration strategy
In the experimental group, NS infusion rate will be adjusted based on LVEDP for the whole duration of the procedure (\<13 mmHg: 5 ml/kg/h; 13-18 mmHg: 3 ml/kg/h; \>18 mmHg: 1.5 ml/kg/h), or for one hour, whichever is the longest. After the procedure, and for a duration of 4 hours, the hydration rate will be adjusted based on the (contrast volume:estimated glomerular filtration rate (eGFR)) ratio, according to the following scheme: 1.5 ml/kg/h if contrast volume/eGFR ratio \<2.0; 3 ml/kg/h for contrast volume/eGFR ratio 2.0-2.9; 5 ml/kg/h for contrast volume/eGFR ratio ≥3.0.
Standard of care
In the control group, infusion rate will be of 1.5 ml/kg/h during the procedure, and for the 4 following hours.
RECRUITING
Montreal Heart Institute, Montreal
Université de Montréal
OTHER
Canadian Institutes of Health Research (CIHR)
OTHER_GOV
Montreal Heart Institute
OTHER