Support for the Resumption of Training of High-level Athletes Post-epidemic COVID-19

NACompletedINTERVENTIONAL
Enrollment

984

Participants

Timeline

Start Date

June 18, 2020

Primary Completion Date

March 2, 2021

Study Completion Date

March 2, 2021

Conditions
COVID-19Myocarditis
Interventions
DIAGNOSTIC_TEST

Resting electrocardiogram

An ECG at rest is performed for all participants at Day 0. A centralized reading is performed by one of the 6 expert cardiologists participating in the research.

DIAGNOSTIC_TEST

Stress test

In case of positive COVID-19 serology and/or positive COVID-19 RT-PCR and/or new ECG abnormality and/or positive questionnaire, a stress test is performed.

DIAGNOSTIC_TEST

Cardiac echocardiography

In case of positive COVID-19 serology and/or positive COVID-19 RT-PCR and/or new ECG abnormality and/or positive questionnaire, a Cardiac echocardiography is performed.

DIAGNOSTIC_TEST

Cardiac rhythm monitoring

In case of positive COVID-19 serology and/or positive COVID-19 RT-PCR and/or new ECG abnormality and/or positive questionnaire, a Cardiac rhythm monitoring is performed.

OTHER

Questionnaire

To determine the rhythmic risk of athletes

DEVICE

Injected Cardiac MRI

"High resolution MRIs is performed on 200 athletes :~* 100 athletes without rhythmic abnormalities (50 individuals with positive COVID-19 status and 50 individuals with negative COVID-19 status)~* 100 athletes with rhythmic abnormalities (50 individuals with positive COVID-19 status and 50 individuals with negative COVID-19 status)"

BIOLOGICAL

Blood sampling for biobank

"For all athletes included at the D0 inclusion visit, a centralized COVID-19 serology is performed to search for biomarkers associated with the occurrence of myocardial fibrosis: analysis of genetic determinants in relation to cardiac damage.~For athletes who have performed MRI: Search for biomarkers associated with the occurrence of myocardial fibrosis: analyses of low-grade inflammation markers (cytokine assay and fibrosis markers)."

Trial Locations (21)

11000

US Carcassonne Rugby training center, Carcassonne

15000

Training Center Stade Aurillacois, Aurillac

16000

Training center Soyaux Angoulême XV Rugby, Angoulême

17000

Stade Rochelais Rugby training center, La Rochelle

19100

CABCL Rugby Training Center, Brive-la-Gaillarde

26100

Training center Valence Romans Drôme Rugby, Romans-sur-Isère

31200

Stade Toulousain Rugby training center, Toulouse

31770

Union Sportive Colomiers Rugby training center, Colomiers

33076

Bordeaux University Hospital - CRB medical office - Hôpital du Tondu, Bordeaux

Bordeaux University Hospital - Service UDH - Hôpital Pellegrin, Bordeaux

33130

Union Bordeaux-Bègles training center, Bègles

38100

FC Grenoble Rugby training center, Grenoble

58000

US Nevers Rugby training center, Nevers

64000

Section Paloise Rugby training center, Pau

64104

Aviron Bayonnais Rugby Pro Training Center, Bayonne

64200

Biarritz Olympique Pays Basque training center, Biarritz

66000

USAP Training Center, Perpignan

75016

Stade Français training center, Paris

81710

Castres Olympique training center, Saïx

82000

AS Montauban Rugby training center, Montauban

92350

Racing92 training center, Le Plessis-Robinson

All Listed Sponsors
lead

University Hospital, Bordeaux

OTHER

NCT04936503 - Support for the Resumption of Training of High-level Athletes Post-epidemic COVID-19 | Biotech Hunter | Biotech Hunter