150
Participants
Start Date
December 20, 2022
Primary Completion Date
October 31, 2026
Study Completion Date
December 31, 2027
Fecal Microbiota Transplantation
"Patients randomized in the FMT group will received FMT within 4 weeks following neutrophils recovery after the allo-HSCT procedure. The stool transplant will be done by enema. The day before FMT, patient will undergo bowel cleansing by ingestion of two liters of polyethylene glycol solution. The day of FMT, a colon cleanse enema will be performed in the morning and FMT will be delivered around two hours after the cleanse enema. This colic preparation is essential to optimize the results of FMT.~The enema (50g of stools diluted in 250mL of NaCl 0.9%) will be performed by a qualified member of the study team (nurse) by using a rectal cannula (within 6 hours of thawing). The enema will have to be kept by the patient for as long as possible and at least 30 minutes."
NOT_YET_RECRUITING
Service d'Hématologie Clinique et Thérapie Cellulaire CHU Amiens Picardie - Site Sud, Amiens
NOT_YET_RECRUITING
Service Maladies du sang CHU Angers, Angers
NOT_YET_RECRUITING
Hématologie clinique CHU Besançon, Besançon
RECRUITING
Plateforme d'Investigation Clinique / Centre d'Investigation Clinique - Inserm 1405, CHU Gabriel Montpied Clermont-Ferrand, Clermont-Ferrand
NOT_YET_RECRUITING
Service de thérapie Cellulaire et d'Hématologie Clinique Adulte CHU Estaing - Clermont-Ferrand, Clermont-Ferrand
NOT_YET_RECRUITING
Service hématologie CHU Grenoble, Grenoble
NOT_YET_RECRUITING
Service des Maladies du sang Hôpital HURIEZ, CHRU de Lille, Lille
NOT_YET_RECRUITING
Service de thérapie cellulaire et l'hématologie clinique adulte CHU Limoges, Limoges
NOT_YET_RECRUITING
Service d'Hématologie Centre Hospitalier Lyon Sud, Lyon
NOT_YET_RECRUITING
Service d'Hématologie et de Médecine interne Hôpital Brabois CHRU Nancy, Nancy
NOT_YET_RECRUITING
Service d'Hématologie Clinique CHU Nantes, Nantes
NOT_YET_RECRUITING
Service d'hématologie clinique, département de greffe de moelle CHU Nice, Nice
NOT_YET_RECRUITING
Service d'Hématologie Adultes Hôpital Necker, Paris
NOT_YET_RECRUITING
Service d'Hématologie clinique Hôpital Pitié-Salpêtrière, Paris
NOT_YET_RECRUITING
Service d'hématologie greffe Hôpital St Louis, Paris
NOT_YET_RECRUITING
Hématologie clinique et thérapie cellulaire Hôpital Haut-Lévèque, Pessac
NOT_YET_RECRUITING
Service d'hématologie greffe Hôpital St Louis, Poitiers
NOT_YET_RECRUITING
Département d'hématologie CAC Rouen, Rouen
NOT_YET_RECRUITING
Hématologie clinique Institut de Cancérologie de la Loire, Saint-Etienne
NOT_YET_RECRUITING
IUC T - Oncopôle, Toulouse
Ministry of Health, France
OTHER_GOV
French Society of Hematology
UNKNOWN
University Hospital, Clermont-Ferrand
OTHER