Study on the Effect of Capacity Shock Intervention Under Goal-directed Hemodynamic Management on P-V Loop

NACompletedINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

June 1, 2020

Primary Completion Date

May 1, 2021

Study Completion Date

June 10, 2021

Conditions
Hemodynamics
Interventions
PROCEDURE

Fluid challenge strategy

Patients received 2ml/kg of succinylateol gelatin within 10 min for fluid shock therapy after grouping, taking SVV as the management target. If SVV\< 13% after shock therapy, the shock therapy was stopped and the infusion was maintained with 4ml/kg/h of crystal solution. If SVV ≥ 13% and ΔSV \<10%, the individual would be excluded from the experiment. If SVV ≥ 13% but ΔSV≥10%, 2ml/kg of succinylateol gelatin was given again within 10 min for liquid shock therapy until SVV\<13%, and 4ml/kg/h of crystal solution was maintained after reaching the target. If SVV≥ 13% after two shock treatments, they were excluded from the experiment. We excluded patients whose intraoperative bleeding ≥400ml and operative time ≥5 hours from the group.

PROCEDURE

conventional strategy

4ml/kg/h of crystal solution was maintained. We excluded patients whose intraoperative bleeding ≥400ml and operative time ≥5 hours from the group.

Trial Locations (1)

510220

Guangzhou Red cross hospital, Guangzhou

All Listed Sponsors
lead

Guangzhou Red Cross Hospital

OTHER

NCT04934761 - Study on the Effect of Capacity Shock Intervention Under Goal-directed Hemodynamic Management on P-V Loop | Biotech Hunter | Biotech Hunter