NCT04926844View on ClinicalTrials.gov

Effectiveness of Combined Levetiracetam and Midazolam in Generalized Convulsive Status Epilepticus in Children

PHASE2CompletedINTERVENTIONAL
Enrollment

144

Participants

Timeline

Start Date

June 20, 2021

Primary Completion Date

August 30, 2022

Study Completion Date

September 1, 2022

Conditions
Status EpilepticusGeneralized Convulsive Status EpilepticusStatus Epilepticus, GeneralizedStatus Epilepticus, Generalized Convulsive
Interventions
DRUG

Levetiracetam

Intravenous levetiracetam 60 mg/kg (max 4500 mg) over 5 minutes (diluted with isotonic saline to a concentration of 50 mg/ml).

DRUG

Midazolam

Intravenous midazolam 0.2 mg/kg (maximum 10 mg) over 2 minutes

DRUG

Placebo

Intravenous isotonic saline (1.2 ml/kg) over 5 minutes

Trial Locations (1)

82524

Department of Pediatrics - Sohag University Hospital, Sohag

All Listed Sponsors
lead

Sohag University

OTHER