Catheter-Related Early Thromboprophylaxis With Enoxaparin Studies

PHASE2/PHASE3RecruitingINTERVENTIONAL
Enrollment

258

Participants

Timeline

Start Date

May 11, 2022

Primary Completion Date

April 30, 2026

Study Completion Date

July 31, 2026

Conditions
Deep Venous Thrombosis
Interventions
DRUG

Enoxaparin

Enoxaparin is a LMWH produced from UFH that exerts its anticoagulant effects by binding to and inducing a conformational change in antithrombin to accelerate the inactivation of factor Xa and thrombin. Age-specified dose of enoxaparin will be administered within 24 hours after insertion of the CVC with the dose subsequently adjusted to pre-specified anti-Xa target.

Trial Locations (22)

10016

RECRUITING

Hassenfeld Children's Hospital, New York

10065

RECRUITING

New York Presbyterian Hospital, New York

10595

RECRUITING

Maria Fareri Children's Hospital, Valhalla

14642

RECRUITING

Golisano Children's Hospital, Rochester

17033

RECRUITING

Penn State Hershey Children's Hospital, Hershey

19104

RECRUITING

Children's Hospital of Philadelphia, Philadelphia

23219

WITHDRAWN

Children's Hospital of Richmond, Richmond

32610

RECRUITING

University of Florida -UF Health, Gainesville

33701

RECRUITING

Johns Hopkins All Children's, St. Petersburg

35233

RECRUITING

Children's of Alabama, Birmingham

43205

WITHDRAWN

Nationwide Children's Hospital, Columbus

44106

RECRUITING

UH Rainbow Babies & Children's Hospital, Cleveland

52242

RECRUITING

Stead Family Children's Hospital, Iowa City

53226

RECRUITING

Children's Hospital Wisconsin, Milwaukee

61637

RECRUITING

Children's Hospital of Illinois at OSF Saint Francis Medical Center, Peoria

63110

RECRUITING

Children's Hospital St. Louis, St Louis

72202

RECRUITING

Arkansas Children's Hospital, Little Rock

73104

RECRUITING

University of Oklahoma, Oklahoma City

75235

RECRUITING

UTSW Medical Center; Children's Medical Center of Dallas, Dallas

78723

RECRUITING

Dell Children's Medical Canter, Austin

80045

RECRUITING

Children's Hospital Colorado, Aurora

06520

RECRUITING

Yale-New Haven Children's Hospital, New Haven

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Children's Hospital Colorado

OTHER

collaborator

Children's Hospital of Philadelphia

OTHER

collaborator

BJC HealthCare

OTHER

collaborator

Medical College of Wisconsin

OTHER

collaborator

Children's of Alabama

OTHER

collaborator

Golisano Children's Hospital

UNKNOWN

collaborator

Maria Fareri Children's Hospital

UNKNOWN

collaborator

Nationwide Children's Hospital

OTHER

collaborator

New York Presbyterian Hospital

OTHER

collaborator

Penn State University

OTHER

collaborator

University of Iowa

OTHER

collaborator

Johns Hopkins All Children's Hospital

OTHER

collaborator

University of Oklahoma

OTHER

collaborator

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

NIH

collaborator

Children's Hospital of Illinois OSF Saint Francis Medical Center

UNKNOWN

collaborator

Hassenfeld Children's Hospital

UNKNOWN

lead

Yale University

OTHER