MicroRNA Correlates of Childhood Maltreatment and Suicidality

RecruitingOBSERVATIONAL
Enrollment

450

Participants

Timeline

Start Date

February 26, 2021

Primary Completion Date

March 31, 2026

Study Completion Date

September 30, 2026

Conditions
Major Depressive DisorderSuicidal Ideation
Interventions
OTHER

Trier Social Stress Test

The TSST is a standardized test to induce acute psychological stress in humans. Participants will abstain from caffeine for 12 hours and nicotine for 2 hours prior to the test. An IV butterfly catheter will be placed in an arm vein and flushed with saline. Participants will rest for 15 minutes. A 10ml baseline blood sample will be drawn. They will perform the TSST task and then have 10ml of blood drawn at 0, 15, 30, 60, and 90 minutes post-TSST.

Trial Locations (2)

35233

RECRUITING

University of Alabama at Birmingham, Birmingham

35294

RECRUITING

UAB Huntsville Regional Medical Campus, Huntsville

All Listed Sponsors
collaborator

National Institute of Mental Health (NIMH)

NIH

lead

University of Alabama at Birmingham

OTHER