Pharmacological Mechanisms of Low-intensity Focused Ultrasound for Motor Cortex Neuroplasticity

EARLY_PHASE1Active, not recruitingINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

May 25, 2021

Primary Completion Date

July 10, 2022

Study Completion Date

May 31, 2026

Conditions
Low Intensity Focussed Ultrasound
Interventions
DRUG

Carbamazepine

600 mg reconstituted as one table. Administered once

DRUG

Lorazepam

2.5 mg mg reconstituted as one table. Administered once

DRUG

Dextromethorphan

150 mgmg reconstituted as one table. Administered once

DRUG

Nimodipine

30 mg reconstituted as one table. Administered once

DRUG

Placebo

Administered once

Trial Locations (1)

M5T 2S8

Toronto Western Hospital, Toronto

All Listed Sponsors
lead

University Health Network, Toronto

OTHER