A Study to Assess the Efficacy and Safety of Ruxolitinib Cream in Children With Atopic Dermatitis (TRuE-AD3)

PHASE3CompletedINTERVENTIONAL
Enrollment

330

Participants

Timeline

Start Date

July 19, 2021

Primary Completion Date

May 10, 2023

Study Completion Date

April 8, 2024

Conditions
Atopic Dermatitis
Interventions
DRUG

Ruxolitinib

The study cream will be applied topically twice a day for up to 52 weeks.

DRUG

Vehicle Cream

Matching vehicle cream will be applied topically twice a day for up to 8 weeks.

Trial Locations (67)

10012

Dr Bobby Buka, Md Greenwich Village, New York

10016

New York University Langone Medical Center-Fink Children'S Ambulatory Care Center, New York

17033

Penn State Milton S. Hershey Medical Center, Hershey

20850

Lawrence J. Green, Md. Llc, Rockville

22015

Pi Coor Clinical Research Llc, Burke

22209

Skindc Clinic, Arlington

23220

Clinical Research Partners Llc, Richmond

29414

Coastal Pediatric Associates, Charleston

29425

Medical University of South Carolina, Charleston

31406

Aeroallergy Research Lab of Savannah, Savannah

33063

Life Clinical Trials Margate, Margate

33142

Acevedo Clinical Research, Miami

33146

Pediatric Center of Excellence Pce Miami Pediatric Endocrinology, Llc, Miami

33155

The Childrens Skin Center Csc Miami, Miami

33156

Entrust Clinical Research, Miami

33173

Ciocca Dermatology Pa, Miami

33624

Forcare Clinical Research, Tampa

33756

Phdermatology, Clearwater

35209

Clinical Research Center of Alabama, Birmingham

35244

Cahaba Dermatology, Hoover

37130

International Clinical Research Tennessee Llc, Murfreesboro

40356

Office of Michael W. Simon, Md, Nicholasville

45414

Ohio Pediatric Research Association, Dayton

46250

Dawes Fretzin Clinical Research Group Llc, Indianapolis

47129

Dermatology Specialists Research Indiana, Clarksville

48202

Henry Ford Medical Center-New Center One, Detroit

48328

Michigan Dermatology Institute, Waterford

53226

Children'S Hospital of Wisconsin, Milwaukee

55905

Mayo Clinic, Rochester

60076

Northshore Medical Group Dermatology Skokie, Skokie

60611

Northwestern Memorial Hospital-Arkes Pavilion, Chicago

61761

Sneeze Wheeze and Itch Associates Llc, Normal

66215

Kansas City Dermatology P.A., Lenexa

68144

Skin Specialists Pc the Advanced Skin Research Center, Omaha

70115

Delricht Research-Touro Medical Center, New Orleans

70808

Meridian Clinical Research, Baton Rouge

70809

Delricht Clinical Research-Clinedge-Ppds Baton Rouge, Baton Rouge

71913

Burke Pharmaceutical Research, Hot Springs

76011

Arlington Research Center, Arlington

76712

Allergy and Asthma Care of Waco, Pa, Waco

78213

Progressive Clinical Research, San Antonio

78218

Texas Dermatology Alamo Heights Office, San Antonio

84020

Intermountain Clinical Research Icr Draper, Draper

84088

Jordan Valley Dermatology Center, West Jordan

84663

Springville Dermatology, Springville

85260

Cct Research With Center For Dermatology and Plastic Surgery, Scottsdale

85295

Physicians Research Group Ii, Gilbert

90017

Iact Health, Los Angeles

Metropolis Dermatology, Los Angeles

90033

University of Southern California, Los Angeles

90045

Dermatology Research Associates, Los Angeles

90404

Clinical Science Institute Clinical Research Specialists Inc, Santa Monica

92262

Palmtree Clinical Research-Clinedge-Ppds, Palm Springs

92506

Integrated Research of Inland, Inc, Riverside

92691

Allergy & Asthma Associates of Southern California, Mission Viejo

92708

First Oc Dermatology, Fountain Valley

93637

Madera Family Medical Group, Madera

97030

Cyn3Rgy Research-Clinedge-Ppds, Gresham

97210

Oregon Dermatology and Research Center, Portland

97239

Knight Cancer Institute At Oregon Health and Science University, Portland

97504

Velocity Clinical Research-Medford, Medford

97527

Velocity Clinical Research Grants Pass Clinical Research Institute of Southern Oregon Pc, Grants Pass

99202

Dermatology Specialists of Spokane, Spokane

02903

Rhode Island Hospital, Providence

T3A 2N1

Dermatology Research Institute, Calgary

L8L 3C3

Leader Research, Hamilton

K2C 3N2

Dermatology Ottawa Research Centre, Ottawa

Sponsors

Lead Sponsor

All Listed Sponsors
lead

Incyte Corporation

INDUSTRY