Tislelizumab in Combination With Sitravatinib in Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer

PHASE3TerminatedINTERVENTIONAL
Enrollment

377

Participants

Timeline

Start Date

July 27, 2021

Primary Completion Date

December 20, 2023

Study Completion Date

December 20, 2023

Conditions
Non-Small Cell Lung Cancer (NSCLC)
Interventions
DRUG

Tislelizumab

200 mg intravenously once every 3 weeks

DRUG

Docetaxel

75 mg/m\^2 intravenously once every 3 weeks

DRUG

Sitravatinib

100 mg orally once daily

Trial Locations (61)

2148

Blacktown Cancer and Haematology Centre, Blacktown

2217

St George Hospital, Kogarah

2487

The Tweed Valley Hospital, Cudgen

2560

Campbelltown Hospital, Campbelltown

3021

Sunshine Hospital, St Albans

3065

St Vincents Hospital Melbourne, Fitzroy

3168

Monash Health, Clayton

4217

Pindara Private Hospital, Benowa

5000

Cancer Research South Australia, Adelaide

100142

Beijing Cancer Hospital, Beijing

100730

Peking Union Medical College Hospital, Beijing

110042

Liaoning Cancer Hospital and Institute, Shenyang

116011

First Affiliated Hospital of Dalian Medical University, Dalian

130021

The First Hospital of Jilin University, Changchun

150000

Harbin Medical University Cancer Hospital, Harbin

200025

Rui Jin Hospital Shanghai Jiao Tong University School of Medicine, Shanghai

200032

Affiliated Zhongshan Hospital of Fudan University, Shanghai

200040

Huashan Hospital Affiliated to Fudan University, Shanghai

210009

Nanjing First Hospital, Nanjing

Zhongda Hospital Southeast University, Nanjing

213003

Changzhou No Peoples Hospital, the Affiliated Hospital of Nanjing Medical University Branch Cheng, Changzhou

215000

The Second Affiliated Hospital of Soochow University, Suzhou

215006

The First Affiliated Hospital of Soochow University, Suzhou

221000

The Affiliated Hospital of Xuzhou Medical University, Xuzhou

230088

Anhui Provincial Cancer Hospital Aka West Branch of Anhui Province Hospital, Hefei

250013

Jinan Central Hospital, Jinan

250117

Shandong Cancer Hospital, Jinan

266000

The Affiliated Hospital of Qingdao University Branch Laoshan, Qingdao

300052

Tianjin Medical University General Hospital, Tianjin

300060

Tianjin Medical University Cancer Institute and Hospital, Tianjin

310016

Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou

310022

Zhejiang Cancer Hospital, Hangzhou

317000

Taizhou Hospital of Zhejiang, Taizhou

330006

The First Affiliated Hospital of Nanchang University Branch Donghu, Nanchang

The Second Affiliated Hospital of Nanchang University, Nanchang

350001

Fujian Provincial Hospital, Fuzhou

350014

Fujian Cancer Hospital, Fuzhou

361003

The First Affiliated Hospital of Xiamen University, Xiamen

400037

Xinqiao Hospital Affiliated to the Army Medical University, Chongqing

400042

Daping Hospital, Third Military Medical University, Chongqing

410011

The Second Xiangya Hospital of Central South University, Changsha

423000

The First Peoples Hospital of Chenzhou, Chenzhou

430022

Union Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan

430030

Tongji Hospital of Tongji Medical College Huazhong University of Science and Technology, Wuhan

430079

Hubei Cancer Hospital, Wuhan

430407

The Second Hospital, University of South China, Hengyang

450000

Henan Cancer Hospital, Zhengzhou

450052

The First Affiliated Hospital of Zhengzhou University, Zhengzhou

510030

Cancer Center of Guangzhou Medical University, Guangzhou

510080

Guangdong Provincial Peoples Hospital, Guangzhou

510515

Nanfang Hospital of Southern Medical University, Guangzhou

515031

Cancer Hospital of Shantou University Medical College, Shantou

518116

Cancer Hospital Chinse Academy of Medical Sciences, Shenzhen Center, Shenzhen

530021

The Peoples Hospital of Guangxi Zhuang Autonomous Region, Nanning

The Tumor Hospital Affiliated to Guangxi Medical University, Nanning

610041

Sichuan Cancer Hospital and Institute, Chengdu

West China Hospital, Sichuan University, Chengdu

650100

Yunnan Cancer Hospital, Kunming

730000

The First Hospital of Lanzhou University, Lanzhou

750004

General Hospital of Ningxia Medical University, Yinchuan

830000

Affiliated Cancer Hospital of Xinjiang Medical University, Ürümqi

Sponsors

Lead Sponsor

All Listed Sponsors
lead

BeiGene

INDUSTRY