NCT04913805 - Matching Perfusion and Metabolic Activity in HFpEF | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

October 11, 2021

Primary Completion Date

May 1, 2027

Study Completion Date

May 1, 2027

Conditions

Heart Failure With Preserved Ejection Fraction

Interventions

DRUG

Potassium Nitrate

Potassium Nitrate is the active intervention that may increase blood flow to exercising muscle

DRUG

Potassium Nitrate + Propionyl-L-Carnitine + Nicotinamide Riboside

Potassium Nitrate + Propionyl-L-Carnitine + Nicotinamide Riboside will be used as a combination intervention to both increase blood flow (KNO3) and mitochondrial function (PLC + NR)

OTHER

Potassium Chloride

Active control

Trial Locations (1)

19104

RECRUITING

University of Pennsylvania, Philadelphia

All Listed Sponsors

lead

University of Pennsylvania

OTHER