Early Tranexamic Acid and Modulating the Inflammatory Response in Sepsis

PHASE3RecruitingINTERVENTIONAL
Enrollment

80

Participants

Timeline

Start Date

June 5, 2021

Primary Completion Date

January 10, 2027

Study Completion Date

January 30, 2027

Conditions
Sepsis
Interventions
DRUG

Tranexamic acid

administer 1 gram of TXA in 100 ml of 0.9% normal saline, intravenous over 10 minutes as soon as possible but no later than three hours after diagnosis, infuse a second gram of TXA IV over 8 hours in 0.9% normal saline for first 3 days.

OTHER

0.9% saline

administer the same volume (100ml normal saline) and same duration (first three days).

Trial Locations (1)

Unknown

RECRUITING

Assiut university hospital, Asyut

All Listed Sponsors
lead

Assiut University

OTHER