Exenatide-test for Diagnosing Endogenous Hyperinsulinemic Hypoglycemia

NACompletedINTERVENTIONAL
Enrollment

29

Participants

Timeline

Start Date

April 29, 2021

Primary Completion Date

April 30, 2024

Study Completion Date

April 30, 2024

Conditions
Endogenous Hyperinsulinism
Interventions
DRUG

Exenatide

"Day1: After a standardized night meal (Maizena 40g plus dessert) at 22 p.m. on the day before, patients receive Exenatide study medication according to the randomization list (injection done slowly over 2 min.). Regular clinical examination of vegetative and neurological state will be done as well as continuous blood sugar measurements and blood withdrawals will be performed.~Day2:~The procedure is equal to study day 1. Instead of Exenatide, a 10ml 0.9% saline solution will be administered intravenously."

DRUG

0.9% saline solution

"Day1: After a standardized night meal (Maizena 40g plus dessert) at 22 p.m. on the day before, patients receive 0.9% saline solution according to the randomization list (injection done slowly over 2 min.). Regular clinical examination of vegetative and neurological state will be done as well as continuous blood sugar measurements and blood withdrawals will be performed.~Day2:~The procedure is equal to study day 1. Instead of 0.9% saline solution, Exenatide will be administered intravenously."

Trial Locations (1)

4031

University Hospital Basel, Division of Nuclear Medicine, Basel

All Listed Sponsors
collaborator

Gottfried und Julia Bangerter- Rhyner-Stiftung, Basel

OTHER

lead

University Hospital, Basel, Switzerland

OTHER