124
Participants
Start Date
May 31, 2021
Primary Completion Date
August 31, 2023
Study Completion Date
August 31, 2028
PD-1 antibody combined with FOLFIRINOX regimen
Give 240 mg of PD-1 antibody before each cycle of chemotherapy, d1; Chemotherapy regimen: irinotecan 150mg/m2, d1; fluorouracil 2400 mg/m², d1-2, continuous pumping for 46 hours; leucovorin 200 mg/m², d1; oxaliplatin 65 mg/m², d1; PD-1 antibody repeats once every 3 weeks; Chemotherapy is repeated every 2 weeks. 4 cycles before surgery. 4 cycles after operation。
PD-1 antibody combined with SOX program
"Give 240 mg of PD-1 antibody before each cycle of chemotherapy, d1; Chemotherapy regimen: oxaliplatin 130 mg/m², d1, ticgio 40-60mg bid, d1-14 q3w;Repeat once every 3 weeks.~2-4 cycles before surgery. The perioperative period was 8 cycles."
RECRUITING
RuiLiu, Tianjin
Tianjin Medical University Cancer Institute and Hospital
OTHER