NCT04908176View on ClinicalTrials.gov

A Drug-drug Interaction Study of Avapritinib and Midazolam

PHASE1CompletedINTERVENTIONAL
Enrollment

10

Participants

Timeline

Start Date

August 24, 2022

Primary Completion Date

March 1, 2024

Study Completion Date

May 10, 2024

Conditions
Gastrointestinal Stromal TumorsGISTNon-resectable Advanced Solid TumorsRecurrent or Unresectable Central Nervous System (CNS) Tumors
Interventions
DRUG

Avapritinib

avapritinib tablets

DRUG

midazolam

midazolam syrup

Trial Locations (3)

19107

Thomas Jefferson University, Sidney Kimmel Cancer Center, Philadelphia

32224

Mayo Clinic Florida, Jacksonville

48103

University of Michigan, Ann Arbor

Sponsors
All Listed Sponsors
lead

Blueprint Medicines Corporation

INDUSTRY